Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. It is active against Gram-negative bacteria and effective against various β-lactamases, including KPC-2, AmpC, OXA-48, and VIM-2. This product is for research use only.
- Reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor.
- Active against gram-negative bacteria.
- Effective against KPC-2, AmpC, OXA-48, and VIM-2 β-lactamases.
- Demonstrated efficacy in neutropenic mouse lung infection and urinary tract infection models.
- Used in combination with cefepime or meropenem for enhanced activity against NDM-1-producing clinical isolates.
- Available documentation includes datasheet, COA, SDS, HNMR, and RP-HPLC.
- For research use only.